Wolff-Kishner Reduction.

CSH Study Web
0
➠It is the reduction of a carbonyl group to the methylene (-CH2) group by the base catalysed decomposition of a hydrazone of a carbonyl group of an aldehyde or a ketone (temperature➞180-200 degree centigrade).
➠E.g.
➠Mechanism:-
➠Modification:-
➥Semi-carbazone and azine are also converted into hydrazone which can be reduced to the methylene group. E.g.
➠Special Features:-
➥This reaction is very specific for the reduction of a carbonyl group and other functional groups present in a molecule remains unaffected.
➥Unlike Clemmenson Reduction, Wolff Kishner Reduction doesn't fail with an acid sensitive and high molecular weight carbonyl compound.
E.g.
➥Wolff Kishner Reduction can also be used for the synthesis of a long chain alkyl group in aromatic rings. E.g.

End

➤Want to get full unit handwritten notes of Named Reactions?

Share

Post a Comment

0Comments

Please don't enter any spam link in the comment box.

Post a Comment (0)